Monday, October 12, 2009

Is Cri Du Chat syndrome a dominant trait or recessive trait?


Answer:
well, i've never heard anyone speak of this an a dominant or recessive trait, instead as a a deletion.
Cri Du Chat is a recessive trait,the short arm is missing one copy of chromosome 5
Toyee...that's wrong. As said before, Cri Du Chat is due to a chromosomal deletion. If you wanted to describe it as dominant or recessive, I guess that you'd have to describe it as dominant. Dominant traits require only one copy in order to see the effects. Recessive traits require two copies (one from mom and one from dad) in order to for the effects to be seen.One more thing...Cri Du Chat usually is de novo (80% of the time). In other words, it happened for the first time in the person who has it. It is not passed on from parent to child. That is because most people who have Cri Du Chat do not have children themselves. There are rare circumstances (familial chromosome translocation) when a parent may have a predisposition to create eggs or sperm with this deletion. Having a chromosome translocation may increase your chance to have a child with a deletion, but you would not describe the inheritance pattern as dominant or recessive.

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