Saturday, October 24, 2009

Is it ok for one person to take trazodone and lexapro?

I have found on the net that some sites tell you there is an interaction with this two drugs?
Please help!
Answer:
Just as long as that person isn't me - then go for it.Ask your doctor.
First, call the doctor, to make sure. Mistakes are made. Every other time I go to the doctors and then the pharmacists, I get different instructions on the pill bottle.Since you're not sure, make sure that you call the doctor and tell them the instructions on the front of the bottle, as well as the pharmaceuticals and their dosage. If the instructions, drug, or dosage ever changes make sure you know WHY. And make sure you take them at the same time every day, or night, as directed. I'm assuming you have a 'day' dose as well as a 'night' dose, so make sure those are spread out evenly, and consistent.But above all, you are supposed to ALWAYS follow the instructions on the label EXACTLY.
"... from a purely pharmacological point of view combining a SSRI antidepressants (lexapro) with a serotonin antagonist (trazodone) will probably result in elevated blood levels of trazodone and its metabolite (mCPP) may increase and cause anxiety. "
Lexapro is a SSRI- selective serotonin reuptake inhibitor
Trazodone is a SRI- serotonin reuptake inhibitorThe SSRIs are the new generation of the classic anti-depressants. On some levels, the two drugs do some of the same thing, so taking them together could have double the therapeutic effect and double the side effects. You might want to check with your doctor and carefully monitor your reaction to observe any adverse effects.However, the major problem in mixing anti-depressants and what you might be thinking of is called serotonin syndrome, which is caused by mixing MAO-I and SRI/SSRI. Since you're not taking a MAO-I there should be no problem there.

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